マイクロ化学

アプリケーションライブラリー

http://park.itc.u-tokyo.ac.jp/kitamori/original.html

説明 詳細
細胞培養/アッセイ ハイドロゲルでの細胞培養 A Microfluidic Hydrogel Capable of Cell Preservation Without Perfusion Culture Under Cell-based Assay Conditions
Yan Xu, Kae Sato, Kazuma Mawatari, Tomohiro Konno, Kihoon Jang, Kazuhiko Ishihara, and Takehiko Kitamori
Advanced Materials, 22, 3017-3021 (2010) (Highlighted on the front inside cover of the journal).
ハイドロゲルでの細胞培養 The biological performance of cell-containing phospholipid polymer hydrogels in bulk and microscale form
Yan Xu, Kihoon Jang, Tomohiro Konno, Kazuhiko Ishihara, Kazuma Mawatari, and Takehiko Kitamori
Biomaterials, 31, 8839-8846(2010).
マイクロチップでの血管組織構築 Cultivation and recovery of vascular endothelial cells in microchannels of a separable micro-chemical chip
Tadahiro Yamashita, Yo Tanaka, Naokazu Idota, Kae Sato, Kazuma Mawatari, and Takehiko Kitamori
Biomaterials, 32, 2459-2465(2011).
マイクロチップでの細胞培養システム Culture and leukocyte adhesion assay of human arterial endothelial cells in a glass microchip
Yo Tanaka, Yuji Kikukawa, Kae Sato, Yasuhiko Sugii, Takehiko Kitamori
Analytical Sciences, 23(3), 261-266 (2007).
マイクロチップでの細胞培養システム-手のひらサイズ A Palmtop-Sized Microfluidic Cell Culture System Driven by a Miniaturized Infusion Pump
N. Sasaki, M. Shinjo, S. Hirakawa, M. Nishinaka, Y. Tanaka, K. Mawatari, T. Kitamori, K. Sato
Electrophoresis, 33(12),1729-1735(2012)
マイクロチップでの細胞培養とせん断応力の影響 Evaluation of effects of shear stress on hepatocytes by a microchip-baesd system
Yuki Tanaka, Masayuki Yamato, Teruo Okano, Takehiko Kitamori, Kiichi Sato
Meas. Sci. Technol. 17, 3167-3170 (2006).
マイクロチップでの細胞培養と熱レンズNO検出 Development of a Microchip-based Bioassay System Using Cultured Cells
M. Goto, K, Sato, A. Murakami, M. Tokeshi, T. Kitamori
Anal. Chem., 77(7), 2125-2131 (2005)
マイクロチップでの細胞培養と熱レンズ分析 Single Cell Analysis by a Scanning Thermal Lens Microscope with a Microchip: Direct Monitoring of Cytochrome-c Distribution During Apoptosis Process
Eiichiro Tamaki, Kiichi Sato, Manabu Tokeshi, Kae Sato, Makoto Aihara, and Takehiko Kitamori
Anal. Chem. 74, 1560-1564 (2002).
マイクロチップでの細胞培養と薬品反応分析 Drug Response Assay System in a Microchip Using Human Hepatoma Cells
Yuki Tanaka, Kiichi Sato, Masayuki Yamato, Teruo Okano, Takehiko Kitamori
Anal. Sci., 20, 411-423 (2004).
マイクロチップでの細胞培養のナノ構造 Micro- and nanometer-scale patterned surface in a microchannel for cell culture in microfluidic devices
Makiko Goto, Takehiko Tsukahara, Kiichi Sato, Takehiko Kitamori
Analytical and Bioanalytical Chemistry, 390(3), 817-823 (2008).
マイクロチップでの細胞培養のパターニング Nanometer-scale Patterned Surfaces for Control of Cell Adhesion
Makiko Goto, Takehiko Tsukahara, Kae Sato, Tomohiro Konno, Kazuhiko Ishihara, Kiichi Sato, Takehiko Kitamori
Analytical Sciences, 23(3), 245-247.

マイクロチップでの細胞培養パターニング-UVパターニング An efficient surface modification using 2-methacryloyloxyethyl phosphorylcholine to control cell attachment via photochemical reaction in a microchannel
Kihoon Jang, Kae Sato, Yo Tanaka, Yan Xu, Moritoshi Sato, Takahiro Nakajima, Kazuma Mawatari, Tomohiro Konno, Kazuhiko Ishihara, and Takehiko Kitamori
Lab on a chip, 10, 1937-1945 (2010).
マイクロチップでの細胞培養パターニング-光リンカー Surface Modification by 2-Methacryloyloxyethyl Phosphorylcholine Coupled to a Photolabile linker for Cell Micropatterning
Kihoon Jang, Kae Sato, Kazuma Mawatari, Tomohiro Konno, Kazuhiko Ishihara, and Takehiko Kitamori
Biomaterials, 30, 1413-1420 (2009).
マイクロチップでの心筋細胞培養 Establishment of a confluent cardiomyocyte culture in a cylindrical microchannel
Yo Tanaka, Hiroto Akaike, Yasuhiko Sugii, Takehiko Kitamori
Analytical Sciences, 27(9), 957-960 (2011)
マイクロチップでの神経細胞培養とグルタミン酸検出 Monitoring of intercellular messengers released from neuron networks cultured in a microchip
Kiichi Sato, Akiko Egami, Tamao Odake, Manabu Tokeshi, Makoto Aihara and Takehiko Kitamori
Journal of Chromatography A, 1111(2), 228-232 (2006).

マイクロチップ細胞培養のためのかん流システム Development of an osteoblast-based 3D continuous-perfusion microfluidic system for drug screening
Kihoon Jang, Kae Sato, Kazuyo Igawa, Ung-il Chung, Takehiko Kitamori
Analytical and Bioanalytical Chemistry, 390(3), 825-832 (2008).
マイクロチップ心筋ポンプ An actuated pump on-chip powered by cultured cardiomyocytes
Y. Tanaka, K. Morishima, T. Shimizu, A. Kikuchi, M. Yamato, T. Okano, and T. Kitamori
Lab on a Chip, 6(3), 362-368 (2006)
マイクロチップ心筋ポンプ A micro-spherical heart pump powered by cultured cardiomyocytes
Yo Tanaka, Kae Sato, Tatsuya Shimizu, Masayuki Yamato, Teruo Okano, Takehiko Kitamori
Lab on a Chip, 7(2), 207-212 (2007).
マイクロチップ心筋ポンプ Fluid actuation for a bio-micropump powered by previously frozen cardiomyocytes directly seeded on a diagonally stretched thin membrane
Yo Tanaka, Yuka Yanagisawa, Takehiko Kitamori
Sensors and Actuators B, 156(1), 494-498 (2011)(Published on the web: 27th April 2011)
マイクロチップ人工腎臓デバイス Basic Structure and Cell Culture Condition of a Bioartificial Renal Tubule on Chip Towards a Cell based Separation Microdevice
Xiaofang GAO, Yo TANAKA, Yasuhiko SUGII, Kazuma MAWATARI, and Takehiko KITAMORI
Analytical Sciences, 27(9), 907(2011)
マイクロチップ単一細胞分析のための細胞吸着法 Development of microfluidic platform for single-cell secretion analysis using a direct photoactive cell-attaching method
Kihoon Jang, Hong Trang Thi Ngo, Yo Tanaka, Yan Xu, Kazuma Mawatari, Takehiko Kitamori
Analytical Sciences, 27(10), 973(2011)(selected as Hot Articles and Cover illustration)
細胞アクチュエーター Demonstration of a PDMS-based bio-microactuator using cultured cardiomyocytes to drive polymer micropillars
Y. Tanaka, K. Morishima, T. Shimizu, A. Kikuchi, M. Yamato, T. Okano, and T. Kitamori
Lab on a Chip, 6(2), 230-235 (2006).
細胞アクチュエーター Demonstration of a bio-microactuator powered by vascular smooth muscle cells coupled to polymer micropillars
Yo Tanaka, Kae Sato, Tatsuya Shimizu, Masayuki Yamato, Teruo Okano, Ichiro Manabe, Ryozo Nagai, and Takehiko Kitamori
Lab on a Chip, 8(1), 58-61 (2008).
ELISA マイクロELISAシステム Microchip-based enzyme-linked immunosorbent assay (microELISA) system with thermal lens detection
K. Sato, M. Yamanaka, T. Hagino, M. Tokeshi, H. Kimura, T. Kitamori
Lab on a Chip, 4(6), 570-575 (2004).
マイクロELISAシステムにIgEアレルギー診断 A Micro-ELISA System for the Rapid and Sensitive Measurement of Total and Specific Immunoglobulin E and Clinical Application to Allergy Diagnosis
Toshinori Ohashi, Kazuma Mawatari, Kae Sato, Manabu Tokeshi, Takehiko Kitamori
Lab on a Chip, 9, 991-995 (2009).
マイクロELISAシステムによるバイオマーカー検出 Micro OS-ELISA: Rapid noncompetitive detection of a small biomarker peptide by open-sandwich ELISA integrated into microfluidic device
M.Ihara, A.Yoshikawa, Y.Wu, H.Takahashi, K.Sato, K.Mawatari, T.Kitamori, and H.Ueda
Lab on a Chip, 10, 92-100 (2010).
マイクロELISAシステムによる口蹄疫ウィルス検出 Determination of Cattle Foot-and-Mouth Disease Virus by micro-ELISA system
Y.Dong, Y. Xu, Z.Liu, Y. Fu, T.Ohashi, K.Mawatari, T.Kitamori
Anal.Sci., 30(3) ,359-363
(selected as Hot Article)
マイクロELISAシステムによる口蹄疫ウィルス検出 Rapid screening swine foot-and-mouth disease virus using micro-ELISA system
Y. Dong, Y.Xu, Z. Liu, Y. Fu, T. Ohashi, Y. Tanaka, K. Mawatari, T.Kitamori
Lab on a Chip, 11, 2153-2155 (2011)
マイクロELISAシステムによる食肉診断 A competitive micro fluidic immunological clenbuterol analysis using a microELISA system
Q.Chen, J.Liu, S.Wang, L.Zhang, Y.Dong, K.Mawatari, T.Kitamori
RSC Advances, 4(75),39894-39896(2014)
マイクロELISAシステムによる毛髪中覚せい剤分析 Rapid analysis of methamphetamine in hair by micropulverized extraction and microchip-based competitive ELISA
Hajime Miyaguchi, Hiroko Takahashi, Toshinori Ohashi, Kazuma Mawatari, Yuko T. Iwata, Hiroyuki Inoue, Takehiko Kitamori
Forensic Science International, 184, 1-5 (2009).
マイクロELISAによるCEAマーカー検出 Determination of Carcinoembryonic Antigen in Human Sera by Integrated Bead-Bed Immunoassay in a Microchip for Cancer Diagnosis
Kiichi Sato, Manabu Tokeshi, Hiroko Kimura, and Takehiko Kitamori
Anal. Chem., 73, 1213-1218 (2001).
マイクロELISAによるIgA検出 Integration of an Immunosorbent Assay System: Analysis of Secretory Human Immunoglobulin A on Polystyrene Beads in a Microchip
Kiichi Sato, Manabu Tokeshi, Tamao Odake, Hiroko Kimura, Takeshi Ooi, Masayuki Nakao, Takehiko Kitamori
Anal. Chem., 72, 1144-1147 (2000).
マイクロELISAによるインターフェロンの同時検出 Microchip-Based Immunoassay System with Branching Multichannels for Simultaneous Determination of Interferon Gamma
Kiichi Sato, Maho Yamanaka, Hiroko Takahashi, Manabu Tokeshi, Hiroko Kimura, and Takehiko Kitamori
Electrophoresis, 23, 734-739 (2002).
熱レンズ検出 熱レンズとマイクロチップ電気泳動 Optimization of An Interface Chip for Coupling Capillary Electrophoresis with Thermal Lens Microscopic Detection
K. Uchiyama, M. Tokeshi, Y. Kikutani, A. Hattori, T. Kitamori
Anal. Sci., 21, 49-52 (2005).
熱レンズとマイクロチップ電気泳動 An Interface Chip Connection between Capillary Electrophoresis and Thermal Lens Microscope
Kenji Uchiyama, Akihide Hibara, Kiichi Sato, Hideaki Hisamoto, Manabu Tokeshi, Takehiko Kitamori
Electrophoresis, 24, 179-184 (2003).
熱レンズと空間分解能 Lateral spatial resolution of thermal lens microscopy during continuous scanning for nonstaining biofilm imaging
T. T. J. Rossteuscher, A. Hibara, K. Mawatari, and T. Kitamori
Journal of Applied Physics, 105, 102030 (2009).
熱レンズと血液透析分析 Analysis of serum proteins adsorbed to a hemodialysis membrane of hollowfiber type by thermal lens microscopy
H. Kimura, H. Kojima, M. Mukaida, T. Kitamori, T. Sawada
Anal. Sci., 15, 1101-1107 (1999).
熱レンズと抗原分布測定 Imaging of Blood Antigen Distribution on Blood Cells by Thermal Lens Microscopy
Hiroko Kimura, Kazuya Sekiguchi, Fumiko Nagao, Masahiro Mukaida, Takehiko Kitamori, Tsuguo Sawada
SPIE,, 278-284 (2000).
熱レンズと細胞内検出 Sub-attomole molecule detection in a single biological cell in-vitro by thermal lens microscopy
M. Harada, M. Shibata, T. Kitamori, T. Sawada
Anal. Sci., 15, 647-650 (1999).
熱レンズと細胞表面分子分布測定 Assay of Spherical Cell Surface Molecules by縲�Thermal Lens Microscopy and Its Application to縲�Blood Cell Substances
Hiroko Kimura, Kazuya Sekiguchi, Takehiko Kitamori, Tsuguo Sawada, Masahiro Mukaida
Anal. Chem., 73, 4333-4337 (2001).
熱レンズと電気泳動 Miniaturized ultrathin slab gel electrophoresis with thermal lens microscope detection and its application to fast genetic diagnosis
JJ. Zheng, T. Odake, T. Kitamori, T. Sawada
Anal. Chem., 71, 5003-5008 (1999).
熱レンズと電気泳動 Fast slab gel electrophoretic separation of DNA fragments with a short migration distance using thermal lens microscope
JJ. Zheng, T. Odake, T. Kitamori, T. Sawada
Anal. Sci., 15, 223-227 (1999).
熱レンズによる1分子検出 Single- and countable-molecule detection of non-fluorescent molecules in liquid phase
M. Tokeshi, M. Uchida, K. Uchiyama, T. Sawada, T. Kitamori
J. Luminescence, 83-4, 261-264 (1999).
熱レンズによる抗原検出 Detection and measurement of a single blood cell surface antigen by thermal lens microscopy
Kimura H, Nagao F, Kitamura A, Sekiguchi K, Kitamori T, Sawada T
Anal. Biochem., 283, 27-32 (2000).
熱レンズ検出 Sub-Single Molecule Determination of Non-Fluorescent Species by Scanning Thermal Lens Microscope and Its Application to Single Cell
Takehiko Kitamori, Marika Uchida, Akiko Egami, Kazuya Sekiguchi, Jinjian Zheng, Tsuguo Sawada, Manabu Tokeshi, Kiichi Sato, Hiroko Kimura
SPIE,, 3922, 67-72 (2000).
光熱免疫分析 Critical increment of Lewis blood group antigen in serum by cancer found by photothermal immunoassay
H. Kimura, T. Kitamori, T. Sawada
Anal. Biochem., 274, 98-103 (1999).
拡張ナノ マイクロ-拡張ナノ空間へのDNA固定化 Serial DNA immobilization in micro- and extended nanospace channels
Bjorn Renberg, Kae Sato, Kazuma Mawatari, Naokazu Idota, Takehiko Tsukahara, and Takehiko Kitamori
Lab on a Chip, 9, 1517-1523 (2009).
拡張ナノELISA Integration of immunoassay into extended nanospace
Ryu Kojima, Kazuma Mawatari, Bjorn Renberg, Takehiko Tsukahara and Takehiko Kitamori
Microchimica Acta, 164, 307-310 (2009).
拡張ナノELISAの分子捕捉 Extended Nanofluidic Immunochemical Reaction with Femtoliter Sample Volumes
Kentaro Shirai, Kazuma Mawatari, Takehiko Kitamori
Small, 10(8),1514-1522(2014)
拡張ナノクロマトグラフィー Femto Liquid Chromatography with Attoliter Sample Separation in the Extended Nanospace Channel
Masaru Kato, Masanori Inaba, Takehiko Tsukahara, Kazuma Mawatari, Akihide Hibara, and Takehiko Kitamori
Analytycal Chemistry, 82(2), 543-547 (2010).
拡張ナノクロマトグラフィー-5mm流路 High Resolution Separation by Pressure-Driven Liquid Chromatography in Meander Extended-Nanochannels
R. Ishibashi, K.Mawatari, T.Kitamori
Journal of Chromatography A, 1238,152-155(2012)
拡張ナノクロマトグラフィーのDIC-TLM検 Femtoliter-Scale Separation and Sensitive Detection of Nonfluorescent Samples in an Extended-Nano Fluidic Device
Hisashi Shimizu, Kazuma Mawatari and Takehiko Kitamori
Analyst, 139(9),2154-2157(2014)
拡張ナノクロマトグラフィーのDIC-TLM検出 Detection of Nonfluorescent Molecules Using Differential Interference Contrast Thermal Lens Microscope for Extended-Nano Channel Chromatography
Hisashi Shimizu, Kazuma Mawatari, Takehiko Kitamori
Journal of Separation Science,34,2920-2924(2012)
拡張ナノクロマトグラフィーの高圧制御システム Development of a Pressure-Driven Injection System for Precisely Time Controlled AttoLiter Sample Injection into Extended Nanochannels
Ryo Ishibashi, Kazuma Mawatari, Katsuyoshi Takahashi, Takehiko Kitamori
Journal of Chromatography A, 1228,51-56(2012)
拡張ナノクロマトグラフィーの順相モード Highly efficient and ultra small volume separation by pressure driven liquid chromatography in extended nanochannels
R. Ishibashi, K.Mawatari, T.Kitamori
Small, 8(8),1237-1242(2012)
(IF=7.3)
拡張ナノ空間の圧力駆動制御と酵素反応 Development of a pressure-driven nanofluidic control system and its application to an enzymatic reaction
Takehiko Tsukahara, Kazuma Mawatari, Akihide Hibara, Takehiko Kitamori
Analytical and Bioanalytical Chemistry, 391(8), 2745-2752 (2008).
表面ナノパターニングと細胞培養 The use of electron beam lithographic graft-polymerization on thermoresponsive polymers for regulating the directionality of cell attachment and detachment
Naokazu Idota, Takahiko Tsukahara, Kae Sato, Teruo Okano, Takehiko Kitamori
Biomaterials, 30, 2095-2101 (2009).
DNA、表面処理、酵素反応
など
マイクロチップRCAとサルモネラ検出 Microbead-based rolling circle amplification in a microchip for sensitive DNA detection
Kae Sato, Atsuki Tachihara, Bjorn Renberg, Kazuma Mawatari, Kiichi Sato, Yuki Tanaka, Jonas Jarvius, Mats Nilsson, and Takehiko Kitamori
Lab on a Chip, 10, 1262-1266 (2010).
マイクロチップRCAとマイクロ流路表面 Single-Molecule DNA Patterning and Detection by Padlock Probing and Rolling Circle Amplification in Microchannels for Analysis of Small Sample Volumes
Yo Tanaka, Hui Xi, Kae Sato, Kazuma Mawatari, Bjorn Renberg, Mats Nilsson, Takehiko Kitamori
Analytical Chemistry, 83(9), 3352-3357(2011)(Published on the web: 4th April 2011)
マイクロチップでの光熱効果による酵素反応制御 Non-Contact Photothermal Control of Enzyme Reaction on a Microchip by Using a Compact Diode Laser
Yuki Tanaka, Maxim N. Slyadnev, Akihide Hibara, Manabu Tokeshi, Takehiko Kitamori
J. Chromatogr. A, 894, 45-51 (2000).
マイクロチップのアフィニティークロマトグラフィーのためのコネクタ On-Chip Connector Valve for Immunoaffinity Chromatography in a Microfluidic Chip
K. Shimura, Y. Koyama, K. Sato, and T. Kitamori
J. Separation Science, 30(10), 1477-1481 (2007).
マイクロチップのマイクロ流路表面生体分子パターニング Micropatterning of biomolecules on a glass substrate in fused silica microchannels by using photolabile linker-based surface activation
Kihoon Jang, Yan Xu, Kae Sato, Yo Tanaka, Kazuma Mawatari, Takehiko Kitamori
Microchimica Acta, 179,49-55(2012)
マイクロチップへのタンパク分子パターニング Graft linker immobilization for spatial control of protein immobilization inside fused microchips
K. Shirai, B. Renberg, K. Sato, K. Mawatari, T. Konno, K. Ishihara, and T. Kitamori.
Electrophoresis, 30(24), 4251-4255 (2009).
マイクロチップ血球分離デバイス Microchip-based Plasma Separation from Whole Blood via Axial Migration of Blood Cells
Arata AOTA, Susumu TAKAHASHI, Kazuma MAWATARI, Yo TANAKA, Yasuhiko SUGII, and Takehiko KITAMORI
Analytical Sciences, 27(12), 1173(2011)(selected as Hot Articles and Cover illustration)
マイクロチップ電気泳動 Isoelectric focusing in a microfluidically defined electrophoresis channel
Kiyohito Shimura, Katsuyoshi Takahashi, Yutaka Koyama, Kae Sato, Takehiko Kitamori
Analytical Chemistry, 80(10), 3818-3823 (2008).

マイクロ空間での酵素反応加速 Acceleration of Enzymatic Reaction in a Microchip
Yuki Tanaka, Maxim N. Slyadnev, Kiichi Sato, Manabu Tokeshi, Haeng-Boo Kim, Takehiko Kitamori
Anal. Sci., 17, 809-810 (2001).
毛管振動によるDNA検出 Highly sensitive and direct detection DNA fragments using a laser-induced capillary vibration effect
T. Odake, K. Tsunoda, T. Kitamori, T. Sawada
Anal. Sci., 17, 95-98 (2001).